Ixekizumab Taltz®
Ixekizumab is a humanised monoclonal antibody directed against interleukin-17A. The SHIKARI® Ixekizumab portfolio supports two distinct research questions: quantitative measurement of ixekizumab concentration and qualitative detection of specific anti-ixekizumab antibodies.
Why Ixekizumab is relevant to biological-drug monitoring research
Ixekizumab has clinically important target biology, indication-specific dosing and measurable systemic exposure, making drug concentration and immunogenicity relevant research variables. Scientific source ↗ · EMA source ↗
Molecular Target & Structure
Ixekizumab is a humanised IgG4 monoclonal antibody that selectively binds and neutralises interleukin-17A. Source ↗
Approved Indications
EMA-authorised uses include plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis and selected juvenile psoriatic/enthesitis-related arthritis populations. EMA source ↗
Plaque-Psoriasis Trough Exposure
FDA pharmacokinetic data show the effect of dosing interval on steady-state trough concentration:
Regulatory exposure values are regimen- and population-specific and are not therapeutic targets. Values vary with dose, timing, formulation and study population. This page is for RUO product information and does not provide clinical guidance.
Two complementary research assays
Enzyme immunoassay for the quantitative determination of ixekizumab in human serum and plasma, developed for concentration measurement between the Cmin and Cmax range.
Enzyme immunoassay for the qualitative determination of specific antibodies to ixekizumab in human serum and plasma. No standard curve is shown because this assay reports a qualitative positive/negative result.
Kit Specifications at a Glance
| Kit Name | Catalog Code | Type | Analyte | ELISA Format | Tests | Storage |
|---|---|---|---|---|---|---|
| SHIKARI® Q-IXE | IXE-FD-TAL | Drug-Level Kit | Ixekizumab | ELISA | 96 | 2–8°C |
| SHIKARI® S-ATIXE | IXE-QLS-TAL | Qualitative ADA Kit | Specific anti-ixekizumab antibodies | ELISA | 96 | 2–8°C |
* Store at +4°C and refer to the current protocol supplied with the kit. Specifications were verified against the official product records.
Which kit fits your research question?
Choose the assay by analyte and measurement mode rather than treating drug concentration and binding antibodies as equivalent.
Ixekizumab Literature and Product-Use Records
Ready to order, or need technical guidance?
Matrix Biotek can help identify the appropriate Ixekizumab assay and prepare regional quotation and delivery information. SHIKARI® products are developed and manufactured in Ankara and supported through our European headquarters in Barcelona.